July 20, 2018
Bulletin interne de l'Institut Pasteur
A breakthrough in understanding the innate immune response activated by dengue and Zika viruses
It is known that the innate immune response is based on the recognition of viral genomes by cellular receptors. By investigating two of these receptors during infection by dengue and Zika viruses, scientists from the Institut Pasteur discovered that a precise region of the viral genome was recognized by a receptor known as RIG-I. Their discovery paves the way for the future development of vaccines for these diseases.