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October 03, 2025

Internal newsletter of the Institut Pasteur

Institut Pasteur
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Press

Blood cancer: a treatment to reprogram the death of cancer cells and alert the immune system

The aim of immunotherapy strategies is to leverage cells in the patient's own immune system to destroy tumor cells. Using a preclinical model, scientists from the Institut Pasteur and Inserm successfully stimulated an effective anti-tumor immune response by reprogramming the death of malignant B cells. They demonstrated an effective triple-therapy approach for treating forms of blood cancer such as certain lymphomas and leukemias which affect B cells. The study was published in the journal Science Advances.

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