TrapBio project, winner of the 5th SESAME Filières call for projects

Set up as part of the regionalized France 2030 program, the “SESAME Filières” call for projects aims to facilitate the development in the Paris Region of partnerships between academic research laboratories and companies, with a view to structuring sectors around technology platforms open to SMEs. Financed on behalf by the French government and the Île-de-France Region and operated by BPIfrance, this call for projects provides support in the form of a grant of up to €2.5 million per project.

For the 5th edition of this call for projects, 3.9 M€ were awarded to 3 projects in the agri-food, digital and healthcare sectors. The TrapBio project led by Milena Hasan, head of the Single Cell Biomarkers platform at the Institut Pasteur, is one of the projects selected, alongside AgriForkTech, led by AgroParisTech, and StartAI@SystemX, supported by the System X Technological Research Institute.

The TraPBio platform will receive 2M€ over 3 years to establish an innovative end-to-end pipeline for biomarker discovery and drug target validation using spatially resolved transcriptomics, targeted proteomics and state-of-the-art single-cell multi-omics phenotyping. To achieve this ambitious aim, 17 Institut Pasteur entities (platforms, research units, directions) will work together to develop modular and highly standardized workflows combining utility from: (1) Bespoke assay design and sample sourcing; (2) ex vivo model derivation; (3) integrated single-cell multi-omics phenotyping; (4) integrated data analyses; (5) valuation. Unique TraPBio modular workflow combinations tailored to specific biological models will be exploitable to the benefit of translational and clinical research areas.

Find out more about Single cell Biomarkers platform

Boosting the scientific and technological competitiveness of the Paris Region

Since 2018, the SESAME Filières funding mechanism has mobilized over €36M to fund 32 projects helping to support the structuring of industries and the scientific and technological competitiveness of players based in Île-de-France.

Two Institut Pasteur projects have already benefited from the SESAME Filières:

In 2018, the project Icypro, coordinated by Jean-Christophe Olivo-Marin (Head of the Bioimage Analysis unit and the director of the institut Carnot Pasteur Microbes & Santé), was funded with the objective to establish an industrial-grade biological image analysis software platform to strengthen the diagnostics, pharmaceuticals and life sciences technology sector  

In 2020, the project PFBioassays, coordinated by Thierry Rose (Head of the Diagnostic Test Innovation and Development Core Facility), was funded which, in the midst of the Covid-19 pandemic, aimed to establish a bioassay technology platform structured to carry out state-of-the-art epidemiological, clinical or scientific studies, and to facilitate the development of innovative bioassays based on breakthrough technologies for prevention, prognosis, diagnosis and therapeutic monitoring.

The next call for projects (AAP 7) is scheduled to run from the beginning of February to the end of April 2025.

Funds will take the form of a grant of up to €2.5 million per project.

Information and application forms can be downloaded from the following address