Phage therapy effective in Crohn's disease

Pathogenic bacteria known as AIEC, which bind to the intestinal mucosa, are frequently found in Crohn's disease patients. Scientists at the Institut Pasteur, in collaboration with scientists from the University of Clermont Auvergne and the Lille Faculty of Pharmaceutical and Biological Sciences, administered a cocktail of bacteriophages orally to murine models for the disease. This led to a reduction in the concentration of AIEC bacteria and to the disappearance of some symptoms, offering new hope for the future treatment of Crohn's disease patients.

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