How the brain detects and regulates inflammation

How does the brain adapt our behavior in response to an infection or injury? A multidisciplinary team of scientists from the Institut Pasteur, CNRS and Inserm have revealed the existence of a circuit involved in sensing and also in the regulation of the anti-inflammatory response orchestrated by different brain regions. This circuit detects inflammation in the blood and organizes and regulates the immune response. It embodies a two-way connection between the brain and immune system. The results were published in the journal Neuron.

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