SpikImm announces the clinical trials start for SPK001, its monoclonal antibody against

SPK001, the first anti-SARS Cov2 monoclonal antibody candidate of SpikImm, a French biotechnology company founded by Truffle Capital, originally discovered by the Institut Pasteur's Human Immunology Laboratory, directed by Dr. Hugo Mouquet (Inserm Joint Research Unit), has been tested on three initial cohorts of healthy volunteers, and has demonstrated excellent tolerance, in the context of the Phase 1 clinical study, recently labeled as a "national priority" by CAPNET (National Steering Committee for Therapeutic Trials and other Research on Covid-19).

SPK001 is a monoclonal antibody developed for the prevention of Covid-19 "pre-exposure prophylaxis" in immunocompromised patients such as organ transplant patients, patients with hematological cancers or autoimmune diseases, who are often unresponsive or poorly responsive to a complete vaccination regimen (approximately 300,000 patients in France, 10 million in Europe and the United States). These patients represent 30 to 40% of all patients hospitalized for Covid-19 with a much higher level of severe forms and mortality than in the general population (risk multiplied by 2 to 4).

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