The Digital Education Hub invites you to register for the fifth edition of the MOOC “Resistance to Antibacterial Agents”, which will be available starting November 3, 2026. This extensively revised version includes 13 new video sessions.  

In 2016, the WHO estimated that if no action is taken, by 2050, 10 million people could die each year from antibiotic-resistant infections. This led it to declare that the emergence and spread of bacteria resistant to antibacterial agents was "a growing threat to public health worldwide, requiring action across all sectors and throughout society". The MOOC Resistance to Antibacterial Agents addresses the major public health problem of the emergence of multi-drug resistant bacteria, responsible for increased morbidity and mortality of a wide range of bacterial infections. 

This MOOC aims to provide basic knowledge on the origin and spread of resistance to antibacterial agents, its identification, and its consequences. It shows the epidemiology of resistance in humans, animals and the environment. It highlights the aggravation of resistance by climate changes, armed conflicts and population displacements. It addresses the concepts to control it, in a "one health" perspective. Finally, this MOOC tries to highlight the alternatives to antibiotics, the latest molecules available and the molecules under development. 

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By the end of this course, you will be able to :  

• Explain how antibiotic resistance emerges and spreads, and its dramatic consequences.
   
• Describe the epidemiology of resistance in humans, animals and the environment.
   
• Apply laboratory methods for diagnosis and identification of antibiotic resistance.
   
• Follow recommendations to prevent the emergence of resistance in humans and farm animals through better control of antibiotic prescribing.
   
• Examine ways of replacing antibiotics or bringing new molecules of antibacterial agents onto the market. 

The MOOC Resistance to Antibacterial Agents is led by :

- Béatrice Berçot, director of the Clinical Bacteriology Laboratory at St. Louis Hospital in Paris and a member of the “Infection, Evolution, and Microbial Modeling” team at Paris-Cité University,

- Philippe Glaser, head of the Ecology and Evolution of Antibiotic Resistance unit, at the Institut Pasteur,

- Didier Mazel, head of the Bacterial Genome Plasticity unit, at the Institut Pasteur.

Moderated by Pedro Dorado-Morales, postdoctoral researcher in the Bacterial Genome Plasticity unit. 

Sign up for this MOOC!   

As a Pasteurian, you can now access all the content of the 24 online courses created by the Institut Pasteur at any time and also benefit from the Institut Pasteur Digital Diploma in Infectious Diseases (DNM2IP) free of charge. 

This MOOC is one of 18 MOOCs accredited for the diploma launched in 2019, which already has more than 3,500 registrants across all continents.

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Access transcripts of content in French: the Boocs    

Are you a French speaker?  No registration required, browse the “Boocs”, for quick access to transcripts of MOOC video sessions! A "booc" is a carefully designed and illustrated PDF file that compiles French subtitles for all MOOC videos. This educational tool is available for 18 MOOCs in the catalog.

Access to “Boocs”