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February 06, 2026

Internal newsletter of the Institut Pasteur

Institut Pasteur
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Neonatal sepsis: using vaginal microbiota to improve predictions

Teams from the Paris Public Hospital Network (AP-HP), Université Paris Cité, Université Sorbonne Paris Nord, Inserm, the Institut Pasteur and FHU Prem'IMPACT, coordinated by Professor Laurent Mandelbrot (Université Paris Cité), Head of the Gynecology and Obstetrics Department at Louis Mourier Hospital (AP-HP), conducted a study to assess whether analyzing bacteria from vaginal swab samples taken at delivery could help predict the risk of neonatal sepsis. The results, published on December 18, 2025 in the American Journal of Obstetrics and Gynecology, show that some identifiable microbial signatures in these samples are associated with a risk of neonatal sepsis.

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