March 17, 2017
Bulletin interne de l'Institut Pasteur
Cellular Therapy: Identification of Circulating Human Innate Lymphoid Cell Precursors
The innate immune response provides an important natural defense system that protects the organism against various types of infectious threats. Innate lymphoid cells (ILCs) are an important cellular actor in these early immune responses. Scientists in the Innate Immunity/Inserm U1223 Unit at the Institut Pasteur have discovered the existence of human ILC precursors (ILCP) that circulate in the blood and are therefore easily obtained. Using purified ILCP, it now becomes possible to generate different types of mature ILCs that could be used in cellular therapies.