July 15, 2022
Bulletin interne de l'Institut Pasteur
Most of our tissues are constantly renewed and need to get rid of dying cells without affecting their organization. A newly identified mechanism is responsible for the seamless exclusion of dying cells from our tissues. This process is based on the dismantling of microtubules, long fibers well known for their function during cell division and transport in the cells. Tuning microtubule stability could be used to exclude cancerous cells from our tissue despite their resistance to cell death.