May 29, 2020
Bulletin interne de l'Institut Pasteur
The Institut Pasteur in Paris and its International Network of 32 institutes have been extremely active worldwide in responding with science to the pandemic caused by the SARS-CoV-2 coronavirus. Its response currently involves a lot of people at the Institut Pasteur in Paris and several teams in the network in other countries. A coronavirus task force was set up by the Institut Pasteur in January to coordinate COVID-19 research by its teams. Nearly 60 projects have benefited from the support of the Institut Pasteur. Many projects are also being carried out in partnerships or with the support of other organizations.
Part of these projects is presented on the pasteur.fr website and will be completed very soon. It is currently divided into eight broad research fields:
Knowledge of the virus and its pathogenesis
Development of research tools
Development of diagnostic tests
Therapeutic research
Vaccine candidates
Epidemiological research
Modeling
Bioinformatics
This week, seven new projects led by the IPIN enrich all of the projects carried out to date:
- inSilico_Drugs_to_Beat_SARS2: accelerating the identification & design of SARS-CoV2 antiviral drugs in combination with the “DrugDesign_SARS2” project (Paris)
- DrugCandidates-SARS-CoV-2: urgent Discovery of Drug Candidates That Target Coronavirus SARS-CoV-2 (INRS Canada)
- isCoVDe – in silico Coronaviruses Decoy: engineering an ACE2 derived polypeptide for label-free, real-time detection on a smartphone device and therapeutic intervention (Montevideo)
- infection spread in Cameroon: evaluation of SARS-CoV-2 infection spread in various populations groups in Cameroon (Cameroon, Paris)
- VacciNanoCor: development of novel nano-based multi-epitope vaccine against coronavirus SARS-CoV-2 - Generation of Humanized NSG transfer mouse model for vaccine testing (Bulgaria)
- Covid-19 & contacts Madagascar: investigation of the first cases of coronavirus (COVID-19) infections and their contacts in Antananarivo, Madagascar (Madagascar)
- COVar_Immune: characterization of variable systemic and mucosal immunity during SARS-CoV-2 infection and recovery (Paris, KKU)
See the latest news on these research projects as of May 28, 2020