Microbiota tailored skin humoral immunity and its potential for the development of novel vaccinal approaches

Scientists have just made two major discoveries about a harmless bacterium, Staphylococcus epidermidis, present on our skin. A first study identifies the skin as a compartment able to develop highly protective antibody responses to skin colonizing microbe in the absence of inflammation or lymph node contribution. A second study concerns the development of a topical vaccine that can be applied directly to the skin, without the need for a needle or an inflammatory reaction.

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