Launch of a clinical study on immune responses for different COVID-19 vaccination regimens (CORSER-4)

The aim of this research led by the Institut Pasteur is to examine and monitor over time the immune system response induced by COVID-19 vaccination for different vaccination regimens. While most people receive two doses of the same vaccine (the "homologous prime-boost" strategy), it is sometimes recommended that some people receive a second dose of a different vaccine from the one used for their first dose (the "heterologous prime-boost" strategy, for example a second dose of an mRNA vaccine after a first dose of an adenovirus vector vaccine). For individuals that have been infected with SARS-CoV-2 in the past, a single vaccine dose is required. Are these different vaccination regimens likely to have a long-term impact on immune responses?

Enrollment in the CORSER-4 study began on June 1 at the Institut Pasteur Medical Center and in the Occupational Health Department. The project is coordinated by Dr. Marie-Charlotte Bernard, a clinical research physician.

People currently being vaccinated can offer to volunteer for this research. All necessary measures will be taken to protect their confidentiality.

Find out more about how to take part